A Bioinformatician/Computational Scientist position open in the MYCimmune program, a research collaborative between the University of Helsinki and University of California, San Francisco (UCSF).
The position is located in the Prof. Juha Klefström’s Lab, Medical Faculty, University of Helsinki. The person chosen for the position will participate in the research group’s daily activities physically in Helsinki and remotely to collaborative efforts with UCSF. The job involves early morning and late evening meetings few times a month.
The main tasks are connected to a 5-year US Department of Defense’s Breast Cancer Research Program, Combining Immunotherapy and MYC Synthetic Lethality for Metastatic Breast Cancer, for which more information can be found on our website www.mycimmune.org.
In the project, we explore MYC-directed synthetic lethal strategies in the scope of drug discovery, pathway dependency identification, and clinical translation. The research involves analysis of complex molecular datasets from in vitro, ex vivo, in vivo models as well as from public databases. For our recent publications, search PubMed for Klefstrom j. Highlighted: Munne et al Nat Comms 2021, Tervonen et al Cancer Res 2021, Haikala Nat Comms 2019, Pant J.Med Chem 2018.
The projects involve statistical and computational analyses of in-house as well as publicly available datasets for generating computational predictions and data visualization relevant to the project’s goals. In addition, we are piloting various processes involving public health and research databases, with intention to integrate the discrete data into meaningful health knowledge.